How can you ensure that biomarkers of interest don’t get lost in the noise?

Nucleic acids in the bloodstream can be powerful biomarkers for tracking tumor presence and progression — if they can be found in the sample. But breakdown during sample collection and handling can make analyzing these hard-to-find nucleic acids even more difficult. 

Nucleic Acid BCT™ is a stabilizing blood collection tube that maintains draw-time concentrations of cell-free DNA, cell-free RNA and extracellular vesicles in venous whole blood samples at room temperature for up to 7 days. The cell-free DNA and cell-free RNA isolated from stored plasma are suitable for
many downstream applications.

HIGHLIGHTS

  • Eliminates the need for immediate plasma preparation (such as tubes containing EDTA) and extends the period between collection and analysis
  • Is compatible with commercially available total plasma nucleic acid isolation kits
  • One plasma isolation protocol for both cell-free DNA and cell-free RNA
  • Stabilizes sample for cell-free DNA, cell-free RNA and extracellular vesicles for up to 7 days of ambient temperature storage.

 

RESOURCES

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